Cyp4a3 - cytochrome P450, family 4, subfamily a, polypeptide 3

Enables alkane 1-monooxygenase activity and arachidonic acid monooxygenase activity. Involved in fatty acid metabolic process; icosanoid biosynthetic process; and kidney development. Located in intracellular membrane-bounded organelle. Biomarker of autosomal recessive polycystic kidney disease. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human CYP4A11 (cytochrome P450 family 4 subfamily A member 11) and CYP4A22 (cytochrome P450 family 4 subfamily A member 22). [provided by Alliance of Genome Resources, Apr 2022]