Ube2a - ubiquitin-conjugating enzyme E2A

Predicted to enable ubiquitin conjugating enzyme activity and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including proteasome-mediated ubiquitin-dependent protein catabolic process; protein ubiquitination; and response to UV. Predicted to act upstream of or within blastocyst hatching; maternal process involved in female pregnancy; and protein ubiquitination. Predicted to be located in XY body and chromatin. Predicted to be part of HULC complex. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Nascimento type. Orthologous to human UBE2A (ubiquitin conjugating enzyme E2 A). [provided by Alliance of Genome Resources, Apr 2022]