Tyrp1 - tyrosinase-related protein 1

Predicted to enable protein homodimerization activity and tyrosinase activity. Predicted to be involved in melanocyte differentiation; melanosome organization; and positive regulation of melanin biosynthetic process. Predicted to act upstream of or within acetoacetic acid metabolic process; melanin metabolic process; and pigmentation. Predicted to be located in clathrin-coated endocytic vesicle membrane; endosome membrane; and melanosome membrane. Predicted to be active in melanosome. Human ortholog(s) of this gene implicated in oculocutaneous albinism; oculocutaneous albinism type III; and pigmentation disease. Orthologous to human TYRP1 (tyrosinase related protein 1). [provided by Alliance of Genome Resources, Apr 2022]