Hdac1 - histone deacetylase 1

Enables DNA-binding transcription factor binding activity; chromatin binding activity; and histone deacetylase activity. Involved in several processes, including positive regulation of cytokine production; regulation of apoptotic process; and regulation of protein modification process. Located in several cellular components, including chromatin; neuron projection; and perinuclear region of cytoplasm. Part of protein-containing complex. Biomarker of pulmonary hypertension. Orthologous to human HDAC1 (histone deacetylase 1). [provided by Alliance of Genome Resources, Apr 2022]