Strap - serine/threonine kinase receptor associated protein

Predicted to enable U2 snRNP binding activity; mRNA binding activity; and signaling receptor binding activity. Predicted to be involved in mRNA splicing, via spliceosome; maintenance of gastrointestinal epithelium; and neuron differentiation. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to be located in cytosol and nucleus. Predicted to be part of SMN complex. Human ortholog(s) of this gene implicated in adenocarcinoma; colorectal carcinoma; large cell carcinoma; lung carcinoma; and squamous cell neoplasm. Orthologous to human STRAP (serine/threonine kinase receptor associated protein). [provided by Alliance of Genome Resources, Apr 2022]