Ppp3r1 - protein phosphatase 3, regulatory subunit B, alpha

Enables phosphoprotein phosphatase activity. Involved in protein dephosphorylation. Predicted to be located in Schaffer collateral - CA1 synapse; parallel fiber to Purkinje cell synapse; and sarcolemma. Predicted to be part of calcineurin complex. Predicted to be active in glutamatergic synapse. Human ortholog(s) of this gene implicated in Alzheimer's disease and dilated cardiomyopathy. Orthologous to human PPP3R1 (protein phosphatase 3 regulatory subunit B, alpha). [provided by Alliance of Genome Resources, Apr 2022]