Alms1 - ALMS1, centrosome and basal body associated protein

Predicted to enable alpha-actinin binding activity and microtubule binding activity. Predicted to be involved in positive regulation of cold-induced thermogenesis and regulation of centriole replication. Predicted to act upstream of or within several processes, including cholesterol homeostasis; gamete generation; and neuron development. Located in centriole and ciliary basal body. Human ortholog(s) of this gene implicated in Alstrom syndrome. Orthologous to human ALMS1 (ALMS1 centrosome and basal body associated protein). [provided by Alliance of Genome Resources, Apr 2022]