Apbb1 - amyloid beta precursor protein binding family B member 1

Enables DNA-binding transcription factor binding activity; amyloid-beta binding activity; and tau protein binding activity. Involved in several processes, including histone H4 acetylation; negative regulation of cell cycle G1/S phase transition; and regulation of nucleobase-containing compound metabolic process. Located in several cellular components, including axon; dendritic spine; and synaptic membrane. Part of protein-containing complex. Is active in presynapse. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human APBB1 (amyloid beta precursor protein binding family B member 1). [provided by Alliance of Genome Resources, Apr 2022]