Kcnj10 - potassium inwardly-rectifying channel, subfamily J, member 10

Enables identical protein binding activity and signaling receptor binding activity. Involved in several processes, including membrane hyperpolarization; potassium ion import across plasma membrane; and response to corticosteroid. Located in several cellular components, including astrocyte projection; basolateral plasma membrane; and microvillus. Used to study diabetic retinopathy. Biomarker of amyotrophic lateral sclerosis; brain disease (multiple); eye disease (multiple); and sensorineural hearing loss. Human ortholog(s) of this gene implicated in EAST syndrome and autosomal recessive nonsyndromic deafness 4. Orthologous to human KCNJ10 (potassium inwardly rectifying channel subfamily J member 10). [provided by Alliance of Genome Resources, Apr 2022]