Kcnj2 - potassium inwardly-rectifying channel, subfamily J, member 2
Alias:
Kir2.1
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Basic Information
Sequence Homology
Transcripts & Proteins
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Predicted to enable identical protein binding activity; phosphatidylinositol-4,5-bisphosphate binding activity; and voltage-gated potassium channel activity. Involved in cellular response to mechanical stimulus; positive regulation of potassium ion transmembrane transport; and regulation of cardiac muscle cell contraction. Located in several cellular components, including T-tubule; endoplasmic reticulum; and intercalated disc. Used to study myocardial infarction. Human ortholog(s) of this gene implicated in Andersen-Tawil syndrome; familial atrial fibrillation; familial periodic paralysis; and short QT syndrome. Orthologous to human KCNJ2 (potassium inwardly rectifying channel subfamily J member 2). [provided by Alliance of Genome Resources, Apr 2022]