Gabrg2 - gamma-aminobutyric acid type A receptor subunit gamma 2

Enables GABA-A receptor activity and chloride channel activity. Contributes to GABA receptor activity. Involved in GABAergic synaptic transmission. Located in cytoplasm; dendrite membrane; and inhibitory synapse. Part of GABA receptor complex. Is active in GABA-ergic synapse and glutamatergic synapse. Is integral component of postsynaptic specialization membrane. Biomarker of hepatic encephalopathy. Human ortholog(s) of this gene implicated in childhood absence epilepsy; developmental and epileptic encephalopathy 74; and familial febrile seizures 8. Orthologous to human GABRG2 (gamma-aminobutyric acid type A receptor subunit gamma2). [provided by Alliance of Genome Resources, Apr 2022]