Gabra6 - gamma-aminobutyric acid type A receptor subunit alpha6

Enables diazepam binding activity and inhibitory extracellular ligand-gated ion channel activity. Contributes to GABA-A receptor activity; GABA-gated chloride ion channel activity; and benzodiazepine receptor activity. Involved in GABAergic synaptic transmission. Located in dendrite; neuronal cell body membrane; and synaptic membrane. Is integral component of plasma membrane. Part of receptor complex. Is active in GABA-ergic synapse; cerebellar Golgi cell to granule cell synapse; and hippocampal mossy fiber to CA3 synapse. Is integral component of postsynaptic specialization membrane. Used to study obesity. Orthologous to human GABRA6 (gamma-aminobutyric acid type A receptor subunit alpha6). [provided by Alliance of Genome Resources, Apr 2022]