Scn11a - sodium voltage-gated channel alpha subunit 11

Predicted to enable voltage-gated sodium channel activity. Predicted to be involved in several processes, including neuronal action potential; regulation of sensory perception of pain; and sodium ion transmembrane transport. Predicted to act upstream of or within sodium ion transport. Located in axon. Is active in glutamatergic synapse. Is integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 3 and hereditary sensory and autonomic neuropathy type 7. Orthologous to human SCN11A (sodium voltage-gated channel alpha subunit 11). [provided by Alliance of Genome Resources, Apr 2022]