Pdk3 - pyruvate dehydrogenase kinase 3

Predicted to enable ATP binding activity; protein serine/threonine kinase activity; and pyruvate dehydrogenase (acetyl-transferring) kinase activity. Involved in cellular response to glucose stimulus. Predicted to be located in nucleolus. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease X-linked dominant 6. Orthologous to human PDK3 (pyruvate dehydrogenase kinase 3). [provided by Alliance of Genome Resources, Apr 2022]