Vav2 - vav guanine nucleotide exchange factor 2

Predicted to enable epidermal growth factor receptor binding activity; guanyl-nucleotide exchange factor activity; and phosphotyrosine residue binding activity. Predicted to be involved in regulation of GTPase activity and regulation of cell size. Predicted to act upstream of or within several processes, including lamellipodium assembly; positive regulation of phosphatidylinositol 3-kinase activity; and small GTPase mediated signal transduction. Predicted to be located in cytoplasm and plasma membrane. Orthologous to human VAV2 (vav guanine nucleotide exchange factor 2). [provided by Alliance of Genome Resources, Apr 2022]