Ptprj - protein tyrosine phosphatase, receptor type, J

Predicted to enable several functions, including beta-catenin binding activity; delta-catenin binding activity; and gamma-catenin binding activity. Predicted to be involved in several processes, including regulation of cell migration; regulation of protein phosphorylation; and regulation of signal transduction. Predicted to act upstream of or within heart development; oligodendrocyte differentiation; and vasculogenesis. Predicted to be located in several cellular components, including cell surface; immunological synapse; and ruffle membrane. Used to study hypertension. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human PTPRJ (protein tyrosine phosphatase receptor type J). [provided by Alliance of Genome Resources, Apr 2022]