Arfgef2 - ADP ribosylation factor guanine nucleotide exchange factor 2

Enables GABA receptor binding activity and myosin binding activity. Involved in exocytosis. Located in several cellular components, including axonemal microtubule; dendritic spine; and trans-Golgi network. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2). [provided by Alliance of Genome Resources, Apr 2022]