Predicted to enable receptor tyrosine kinase binding activity and transmembrane receptor protein tyrosine kinase activator activity. Predicted to be involved in several processes, including positive regulation of peptidyl-tyrosine phosphorylation; regulation of angiogenesis; and regulation of blood vessel endothelial cell migration. Predicted to act upstream of or within Notch signaling pathway. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Orthologous to human ANGPT4 (angiopoietin 4). [provided by Alliance of Genome Resources, Apr 2022]