Atp2b4 - ATPase plasma membrane Ca2+ transporting 4

Enables P-type calcium transporter activity; PDZ domain binding activity; and protein kinase binding activity. Involved in several processes, including calcium ion transport; hippocampus development; and negative regulation of calcineurin-NFAT signaling cascade. Located in basolateral plasma membrane; neuron projection; and sperm principal piece. Is active in glutamatergic synapse. Is integral component of presynaptic active zone membrane. Biomarker of dystonia. Orthologous to human ATP2B4 (ATPase plasma membrane Ca2+ transporting 4). [provided by Alliance of Genome Resources, Apr 2022]