Scn10a - sodium voltage-gated channel alpha subunit 10

Enables voltage-gated sodium channel activity. Involved in odontogenesis of dentin-containing tooth; sensory perception of pain; and sodium ion transport. Located in axon. Is integral component of membrane. Part of clathrin complex. Is active in glutamatergic synapse. Is integral component of presynaptic membrane. Used to study sciatic neuropathy. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 2. Orthologous to human SCN10A (sodium voltage-gated channel alpha subunit 10). [provided by Alliance of Genome Resources, Apr 2022]