Predicted to enable ubiquitin binding activity; ubiquitin protein ligase binding activity; and ubiquitin-like protein transferase activity. Predicted to be involved in ISG15-protein conjugation; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within modification-dependent protein catabolic process. Predicted to be part of ubiquitin ligase complex. Predicted to be active in nucleus. Orthologous to human UBE2L6 (ubiquitin conjugating enzyme E2 L6). [provided by Alliance of Genome Resources, Apr 2022]