Ttc21b - tetratricopeptide repeat domain 21B

Predicted to enable chromatin binding activity. Predicted to be involved in intraciliary retrograde transport; protein localization to cilium; and regulation of intraciliary retrograde transport. Predicted to act upstream of or within several processes, including central nervous system development; regulation of gene expression; and regulation of signal transduction. Predicted to be located in cilium. Predicted to be part of intraciliary transport particle A. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 4 and nephronophthisis 12. Orthologous to human TTC21B (tetratricopeptide repeat domain 21B). [provided by Alliance of Genome Resources, Apr 2022]