Eef2 - eukaryotic translation elongation factor 2

Enables several functions, including 5S rRNA binding activity; actin filament binding activity; and p53 binding activity. Involved in several processes, including cellular response to brain-derived neurotrophic factor stimulus; positive regulation of cytoplasmic translation; and response to ischemia. Located in cytosol; membrane raft; and polysomal ribosome. Part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in glaucoma and spinocerebellar ataxia type 26. Orthologous to human EEF2 (eukaryotic translation elongation factor 2). [provided by Alliance of Genome Resources, Apr 2022]