Aldh2 - aldehyde dehydrogenase 2 family member

Enables NADH binding activity; aldehyde dehydrogenase (NAD+) activity; and identical protein binding activity. Involved in several processes, including behavioral response to ethanol; cellular response to resveratrol; and response to ischemia. Located in mitochondrial matrix. Biomarker of heart disease. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; artery disease (multiple); diabetes mellitus (multiple); diabetic neuropathy; and liver disease (multiple). Orthologous to human ALDH2 (aldehyde dehydrogenase 2 family member). [provided by Alliance of Genome Resources, Apr 2022]