Enables NADHX epimerase activity and NADPHX epimerase activity. Predicted to be involved in several processes, including membrane raft distribution; negative regulation of angiogenesis; and regulation of cholesterol efflux. Predicted to be located in several cellular components, including cell body; cilium; and extracellular space. Predicted to be active in mitochondrion. Orthologous to human NAXE (NAD(P)HX epimerase). [provided by Alliance of Genome Resources, Apr 2022]