Spart - spartin

Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in abscission; cell division; and negative regulation of BMP signaling pathway. Predicted to act upstream of or within several processes, including adipose tissue development; lipid droplet organization; and negative regulation of collateral sprouting in absence of injury. Predicted to be located in several cellular components, including lipid droplet; midbody; and mitochondrial outer membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Troyer syndrome. Orthologous to human SPART (spartin). [provided by Alliance of Genome Resources, Apr 2022]