Smc3 - structural maintenance of chromosomes 3

Predicted to enable several functions, including beta-tubulin binding activity; cohesin loading activity; and dynein complex binding activity. Predicted to be involved in meiotic cell cycle; mitotic nuclear division; and regulation of DNA replication. Predicted to act upstream of or within stem cell population maintenance. Located in basement membrane. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 3. Orthologous to human SMC3 (structural maintenance of chromosomes 3). [provided by Alliance of Genome Resources, Apr 2022]