Rgs4 - regulator of G-protein signaling 4

Enables G-protein alpha-subunit binding activity and GTPase activator activity. Involved in several processes, including regulation of ion transport; regulation of signal transduction; and response to alkaloid. Located in cytosol; nucleus; and plasma membrane. Part of protein-containing complex. Used to study epilepsy. Biomarker of bladder disease; hypertension; lesion of sciatic nerve; opioid abuse; and status epilepticus. Orthologous to human RGS4 (regulator of G protein signaling 4). [provided by Alliance of Genome Resources, Apr 2022]