Skp2 - S-phase kinase associated protein 2

Predicted to enable identical protein binding activity. Involved in cellular response to cell-matrix adhesion and positive regulation of smooth muscle cell proliferation. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytosol and nucleus. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in prostate carcinoma. Orthologous to human SKP2 (S-phase kinase associated protein 2). [provided by Alliance of Genome Resources, Apr 2022]