Tle5 - TLE family member 5, transcriptional modulator

Predicted to enable identical protein binding activity and transcription corepressor activity. Predicted to be involved in several processes, including negative regulation of macromolecule metabolic process; positive regulation of anoikis; and response to interleukin-1. Predicted to act upstream of or within several processes, including cellular response to extracellular stimulus; regulation of transcription, DNA-templated; and skeletal system development. Located in nucleus. Orthologous to human TLE5 (TLE family member 5, transcriptional modulator). [provided by Alliance of Genome Resources, Apr 2022]