Map1b - microtubule-associated protein 1B

Enables actin binding activity; microtubule binding activity; and phospholipid binding activity. Involved in several processes, including induction of synaptic plasticity by chemical substance; nervous system development; and regulation of microtubule polymerization or depolymerization. Located in several cellular components, including axon; dendrite; and perikaryon. Part of microtubule associated complex. Biomarker of hypothyroidism and visual epilepsy. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human MAP1B (microtubule associated protein 1B). [provided by Alliance of Genome Resources, Apr 2022]