Rasgrp1 - RAS guanyl releasing protein 1

Predicted to enable several functions, including cation binding activity; diacylglycerol binding activity; and guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including positive regulation of cytokine production; positive regulation of intracellular signal transduction; and positive regulation of lymphocyte differentiation. Predicted to act upstream of or within several processes, including activation of GTPase activity; mast cell degranulation; and regulation of phosphatidylinositol 3-kinase signaling. Predicted to be located in Golgi apparatus; cytosol; and plasma membrane. Human ortholog(s) of this gene implicated in immunodeficiency 64. Orthologous to human RASGRP1 (RAS guanyl releasing protein 1). [provided by Alliance of Genome Resources, Apr 2022]