Aif1 - allograft inflammatory factor 1

Predicted to enable actin filament binding activity and calcium ion binding activity. Involved in several processes, including cellular response to morphine; positive regulation of muscle hyperplasia; and positive regulation of nitrogen compound metabolic process. Located in cytosol; lamellipodium; and perikaryon. Used to study type 1 diabetes mellitus. Biomarker of brain disease (multiple); glomerulonephritis; meningoencephalitis; and motor neuron disease. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human AIF1 (allograft inflammatory factor 1). [provided by Alliance of Genome Resources, Apr 2022]