Ppt1 - palmitoyl-protein thioesterase 1

Predicted to enable lysophosphatidic acid binding activity; sulfatide binding activity; and thiolester hydrolase activity. Predicted to be involved in several processes, including lysosomal lumen acidification; positive regulation of endocytosis; and protein depalmitoylation. Predicted to act upstream of or within several processes, including grooming behavior; regulation of phospholipase A2 activity; and visual perception. Located in several cellular components, including lysosome; neuronal cell body; and synaptic vesicle. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 1. Orthologous to human PPT1 (palmitoyl-protein thioesterase 1). [provided by Alliance of Genome Resources, Apr 2022]