Mag - myelin-associated glycoprotein

Enables carboxylic acid binding activity; protein kinase binding activity; and signaling receptor binding activity. Involved in several processes, including cellular response to mechanical stimulus; negative regulation of neuron differentiation; and regulation of neurogenesis. Located in several cellular components, including Schmidt-Lanterman incisure; mesaxon; and myelin sheath adaxonal region. Is integral component of plasma membrane. Used to study middle cerebral artery infarction and sciatic neuropathy. Biomarker of nerve compression syndrome. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 75. Orthologous to human MAG (myelin associated glycoprotein). [provided by Alliance of Genome Resources, Apr 2022]