Macroh2a1 - macroH2A.1 histone

Predicted to enable several functions, including DNA binding activity; promoter-specific chromatin binding activity; and protein serine/threonine kinase inhibitor activity. Predicted to be involved in several processes, including negative regulation of macromolecule metabolic process; positive regulation of cell differentiation; and regulation of response to oxidative stress. Predicted to act upstream of or within dosage compensation; negative regulation of transcription by RNA polymerase II; and regulation of lipid metabolic process. Located in chromatin and nucleus. Part of nucleosome. Orthologous to human MACROH2A1 (macroH2A.1 histone). [provided by Alliance of Genome Resources, Apr 2022]