Tcirg1 - T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3

Predicted to enable ATPase binding activity. Predicted to be involved in vacuolar acidification. Predicted to act upstream of or within several processes, including T cell activation; animal organ development; and cellular cation homeostasis. Predicted to be located in several cellular components, including apical plasma membrane; cytoplasmic vesicle; and lysosome. Predicted to be part of vacuolar proton-transporting V-type ATPase complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 1. Orthologous to human TCIRG1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3). [provided by Alliance of Genome Resources, Apr 2022]