Serpinh1 - serpin family H member 1

Predicted to enable serine-type endopeptidase inhibitor activity and unfolded protein binding activity. Predicted to be involved in collagen fibril organization and negative regulation of endopeptidase activity. Predicted to act upstream of or within chondrocyte development involved in endochondral bone morphogenesis; collagen biosynthetic process; and protein maturation. Predicted to be located in endoplasmic reticulum-Golgi intermediate compartment and membrane raft. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 10 and preterm premature rupture of the membranes. Orthologous to human SERPINH1 (serpin family H member 1). [provided by Alliance of Genome Resources, Apr 2022]