Sigmar1 - sigma non-opioid intracellular receptor 1

Enables G protein-coupled opioid receptor activity. Involved in nervous system development. Predicted to be located in membrane; nuclear envelope; and postsynaptic density. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 16 and distal spinal muscular atrophy 2. Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1). [provided by Alliance of Genome Resources, Apr 2022]