Plcb3 - phospholipase C beta 3

Enables phosphatidylinositol phospholipase C activity. Involved in several processes, including inositol trisphosphate metabolic process; phosphatidylinositol catabolic process; and phosphatidylinositol-mediated signaling. Located in cytosol and sarcolemma. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia with corneal dystrophy. Orthologous to human PLCB3 (phospholipase C beta 3). [provided by Alliance of Genome Resources, Apr 2022]