Mesp2 - mesoderm posterior bHLH transcription factor 2

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including mesoderm formation; regulation of transcription by RNA polymerase II; and somite rostral/caudal axis specification. Predicted to act upstream of or within several processes, including mesodermal cell migration; regulation of gene expression; and somitogenesis. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Orthologous to human MESP2 (mesoderm posterior bHLH transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]