Sipa1l3 - signal-induced proliferation-associated 1 like 3

Predicted to enable GTPase activator activity. Predicted to be involved in several processes, including activation of GTPase activity; epithelial cell morphogenesis; and establishment of epithelial cell polarity. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in several cellular components, including nucleoplasm; stress fiber; and tricellular tight junction. Predicted to be active in Golgi apparatus and plasma membrane. Human ortholog(s) of this gene implicated in cataract 45. Orthologous to human SIPA1L3 (signal induced proliferation associated 1 like 3). [provided by Alliance of Genome Resources, Apr 2022]