Spr - sepiapterin reductase

Enables sepiapterin reductase activity. Involved in response to organic substance and tetrahydrobiopterin biosynthetic process. Predicted to be located in cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in dystonia and sepiapterin reductase deficiency. Orthologous to human SPR (sepiapterin reductase). [provided by Alliance of Genome Resources, Apr 2022]