Enables carbonate dehydratase activity. Involved in animal organ development; response to steroid hormone; and response to xenobiotic stimulus. Located in apical plasma membrane; sarcolemma; and sarcoplasmic reticulum. Human ortholog(s) of this gene implicated in retinitis pigmentosa. Orthologous to human CA4 (carbonic anhydrase 4). [provided by Alliance of Genome Resources, Apr 2022]