Penk - proenkephalin

Predicted to enable opioid receptor binding activity. Involved in several processes, including cellular response to organic cyclic compound; general adaptation syndrome, behavioral process; and locomotory exploration behavior. Located in several cellular components, including cell body fiber; perikaryon; and symmetric synapse. Is active in neuronal dense core vesicle lumen and synaptic vesicle lumen. Used to study heroin dependence. Biomarker of Parkinson's disease; alcohol use disorder; dystonia; and spinal disease. Orthologous to human PENK (proenkephalin). [provided by Alliance of Genome Resources, Apr 2022]