Tubb5 - tubulin, beta 5 class I

Enables GTPase activating protein binding activity and protein domain specific binding activity. Predicted to be involved in microtubule cytoskeleton organization; mitotic cell cycle; and regulation of synapse organization. Predicted to act upstream of or within spindle assembly. Located in membrane raft. Part of protein-containing complex. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 6 and congenital symmetric circumferential skin creases 1. Orthologous to human TUBB (tubulin beta class I). [provided by Alliance of Genome Resources, Apr 2022]