Epha3 - Eph receptor A3

Predicted to enable GPI-linked ephrin receptor activity; growth factor binding activity; and transmembrane-ephrin receptor activity. Involved in fever generation; response to cytokine; and response to lipopolysaccharide. Predicted to be located in several cellular components, including GABA-ergic synapse; early endosome; and nucleus. Predicted to be part of receptor complex. Predicted to be active in neuron projection and presynapse. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human EPHA3 (EPH receptor A3). [provided by Alliance of Genome Resources, Apr 2022]