Nup133 - nucleoporin 133

Predicted to be a structural constituent of nuclear pore. Predicted to be involved in several processes, including nuclear pore organization; nucleocytoplasmic transport; and transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery. Predicted to act upstream of or within nervous system development; paraxial mesoderm development; and somite development. Predicted to be located in nuclear membrane. Predicted to be part of nuclear pore outer ring. Predicted to colocalize with kinetochore. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome and nephrotic syndrome type 18. Orthologous to human NUP133 (nucleoporin 133). [provided by Alliance of Genome Resources, Apr 2022]