Enables epidermal growth factor receptor binding activity and growth factor activity. Involved in several processes, including negative regulation of osteoblast differentiation; neurogenesis; and response to cAMP. Located in extracellular space. Used to study high grade glioma. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human AREG (amphiregulin). [provided by Alliance of Genome Resources, Apr 2022]