Enables deoxycytidine kinase activity and thymidine kinase activity. Involved in deoxycytidine metabolic process and thymidine metabolic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 3 and mitochondrial DNA depletion syndrome 2. Orthologous to human TK2 (thymidine kinase 2). [provided by Alliance of Genome Resources, Apr 2022]